Methyl 2-(2-chlorophenyl)-2-hydroxyacetate

Methyl 2-(2-chlorophenyl)-2-hydroxyacetate - Names and Identifiers

Name	Methyl 2-(2-chlorophenyl)-2-hydroxyacetate
Synonyms	rac-methyl2-chloromandelate Methyl 2-(2-chlorophenyl)-2-hydroxyacetate Benzeneacetic acid, 2-chloro-a-hydroxy-, Methyl ester
CAS	156276-21-0

Methyl 2-(2-chlorophenyl)-2-hydroxyacetate - Physico-chemical Properties

Molecular Formula	C9H9ClO3
Molar Mass	200.62
Density	1.316±0.06 g/cm3(Predicted)
Boling Point	134-136 °C(Press: 6 Torr)
pKa	11.82±0.20(Predicted)

Methyl 2-(2-chlorophenyl)-2-hydroxyacetate - Upstream Downstream Industry

Downstream Products

Methyl 2-(2-chlorophenyl)-2-oxoacetate
2-ChloroMandelic Acid Methyl Ester
2-CHLORO-MANDELIC ACID METHYL ESTER

Methyl 2-(2-chlorophenyl)-2-hydroxyacetate - Introduction

Methyl 2-(2-chlorophenyl)-2-hydroxyacetate is an organic compound with the chemical formula C9H9ClO3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-Density: 1.304g/cm3
-Melting point:-18 ° C
-Boiling point: 312 ° C
-Solubility: Soluble in organic solvents such as alcohol, ether and acetic acid, slightly soluble in water

Use:
Methyl 2-(2-chlorophenyl)-2-hydroxyacetate can be used as an important organic synthesis intermediate, which has a wide range of applications in drug synthesis, Pesticide Synthesis and dye synthesis. It is commonly used in the synthesis of steroid drugs, ketocoumarin and other organic compounds.

Method:
Methyl 2-(2-chlorophenyl)-2-hydroxyacetate can be formed by the reaction of 2-chlorobenzoic acid and methanol under the action of a catalyst.

Safety Information:
Methyl 2-(2-chlorophenyl)-2-hydroxyacetate has no obvious harm under normal conditions. However, as an organic compound, it still needs to be handled properly. During the operation, care should be taken to avoid direct contact with skin, eyes and respiratory tract, and take appropriate protective measures, such as wearing gloves, goggles and protective masks. In case of accidental contact, rinse immediately with plenty of water. During use or storage, keep away from fire and high temperature, and maintain a well-ventilated environment.

Last Update：2024-04-09 20:45:29